Tigers vs. Guardians May 21: AL Central Clash and Betting Guide

Tigers vs. Guardians May 21: AL Central Clash and Betting Guide

By Michael Peterson

February 16, 2025 at 08:33 AM

The Detroit Tigers (13-26) face the Cleveland Guardians (17-19) in the second game of their three-game series at Progressive Field on Saturday, May 21 at 6:10 PM ET. The Guardians won the series opener 6-1.

Key Matchup Details:

  • Pitching: Alex Faedo (0-1, 2.87 ERA) vs Shane Bieber (1-2, 3.72 ERA)
  • Odds: Guardians -190, Tigers +160
  • Run Line: Tigers +1.5 (-142)
  • Over/Under: 8 runs

Team Comparison:

  • Scoring: Guardians 4.66 runs/game (7th MLB), Tigers 2.76 runs/game (last)
  • Defense: Tigers allow 3.92 runs/game (10th), Guardians allow 4.60 runs/game (25th)
  • Home/Road: Guardians 8-7 at home, Tigers 4-13 on road

Key Players:

  • Guardians: Jose Ramirez (.287, 9 HR, 37 RBI)
  • Tigers: Miguel Cabrera (.276, 3 HR, 14 RBI)

Notable Trends:

  • Guardians are 15-5 in last 20 home games vs Tigers
  • Guardians are 8-3 in last 11 vs AL Central teams
  • Tigers struggling with MLB-worst record and 4-13 road record

The Guardians look to secure the series win behind ace Shane Bieber against a struggling Tigers team that has particularly struggled on the road this season. Cleveland's superior offense and strong home record against Detroit make them clear favorites.

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