
McNeese vs Clemson Odds, Picks & Betting Preview: March Madness Round of 64 Clash
McNeese State (27-6, 15-17 ATS) faces Clemson Tigers (27-6, 20-13 ATS) in a compelling #12 vs #5 March Madness matchup. The game tips off at 3:15 pm ET from Amica Mutual Pavilion in Providence, Rhode Island.

Basketball player wearing Phoenix Suns uniform
Current Betting Odds:
- McNeese: +275 (Underdog)
- Clemson: -7.5 (Favorite)
McNeese State's Strengths:
- 22-1 record in last 23 games
- 18th in opponent turnover percentage (21.6%)
- 42nd in offensive rebounding
- 11th in steal percentage (13.3%)
- Strong three-point defense (32% opponent shooting)
- 63rd in offensive efficiency
- 66th in defensive efficiency
Clemson's Key Factors:
- Won 10 of last 11 games
- Chase Hunter averaging 16.4 PPG
- 64th in effective field goal percentage (53.6%)
- 31st in three-point shooting (37%)
- Weakness: 191st in opponent offensive rebounding
Analysis: McNeese's pressure defense and turnover-forcing ability matches well against Clemson's 15.7% turnover rate. The Cowboys' strong three-point defense could neutralize Clemson's perimeter shooting advantage. While undersized, McNeese's aggressive rebounding and defensive pressure make them a dangerous underdog.
Prediction: McNeese's defensive prowess and ability to create extra possessions through turnovers and offensive rebounds should keep this game close. Their effective three-point defense will be crucial against Clemson's shooting.
Best Bet: McNeese Moneyline (+275) at DraftKings
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