
Clemson vs Louisville ACC Semis: Odds, Props & How to Bet This Battle of Top-15 Teams
The #10 Clemson Tigers (27-5) face the #13 Louisville Cardinals (26-6) in the ACC Tournament semifinal, with Clemson entering as 1-point favorites. Both teams boast impressive 18-2 conference records and recent hot streaks - Louisville has just one loss in their last 21 games, while Clemson has two in their last 20.

College players in white uniforms
Key Game Information:
- Time: 9:30pm ET
- Location: Spectrum Center, Charlotte, NC
- TV: ESPN
- Spread: Clemson -1
- Total: 141.5
- Moneyline: Clemson -120, Louisville +100
Recent Form:
- Louisville: Won 10 straight (6-4 ATS), including a narrow 75-73 win over Stanford
- Clemson: Won 9 straight, coming off a season-low scoring output in 57-54 win vs SMU
Key Player Props:
- Chucky Hepburn (LOU): 17.5 points, 5.5 assists
- Terrance Edwards (LOU): 17.5 points
- Chase Hunter (CLEM): 15.5 points
- Ian Schieffelin (CLEM): 8.5 rebounds
Team Comparisons:
- KenPom Rankings: Clemson #19, Louisville #25
- Offensive Efficiency: Clemson #21, Louisville #27
- Defensive Efficiency: Clemson #17, Louisville #23
- Scoring: Louisville 79.2 PPG, Clemson 76.4 PPG
- Defense: Clemson 65.3 PPG allowed, Louisville 68.7 PPG allowed
Previous Meeting: Louisville won 74-64 behind J'Vonne Hadley's 32 points and 10 rebounds. The Cardinals' advantage at the free throw line (16-20 vs 4-5) proved decisive.
The Pick: Clemson -1 (-112) Reasoning: Clemson's ACC-best 17-9 ATS record as favorites and strong defensive metrics give them a slight edge in what projects to be a closely contested game.